Compared to the genomes of model plants Arabi-dopsis thaliana and rice, each wheat genome is an order of magnitude larger. Indirect evidence suggests that in the wheat genomes there may be gene-rich islands (gene insulae) separated by gene-poor or gene-empty regions. The goal of this project is to obtain a detailed picture of gene distribution in the wheat D genome and arrive at understanding of the evolution of the global organization of large genomes.

To assess gene distribution across the D-genome chromosomes, we exploit the fact that the Aegilops tauschii genome is completely homologous with the D genome of wheat. Physical maps of each of the seven Ae. tauschii chromosomes will be constructed and a large number of gene loci will be placed on the physical maps. The physical maps will be integrated with the wheat linkage and deletion maps. The distribution of loci integrated into the physical maps will be used to assess the distribution of genes in the D-genome and the distribution and characteristics of gene insulae. The physical maps of the D-genome chromosomes will be compared with the maize phys-ical map and the rice genomic sequence. These comparisons may shed light on the evolution of the global structure of large cereal genomes. The identification and mapping of gene insulae in the wheat D genome will facilitate the discovery and isolation of economically important genes, ultimately allowing the sequencing of the most relevant regions of wheat genomes.

 
What's New
Nov, 2004: New assembles of wheat D genome FPC contigs are available in WheatDB. The assembly includes 7 version based on the different parameters and merging methods.Also new EST markers have been added.
Hybridization filters and BAC/BIBAC libraries for wheat D genome are available for request. Please contact Alina Akhunova (E-mail: arakhunova@ucdavis.edu) for details.
GenoProfiler (v2.0): a cross-platform software package for the fully automated processing of fingerprinting data from ABI 3100/3700 Genetic Analyzer. It's avaliable for request now. Please visit GenoProfiler page.

FPViewer(v1.0) is available to view fingerprints, matched bands and Sulston scores of a contig inWheatDB Browser.
BAC clone trace files are available and can be viewed by TraceViewer (v1.0) tool in WheatDB Browser.
WheatDB is wheat D-genome physical mapping database which contains BAC libraries, clone fingerprints, trace files, markers and contigmaps. The WheatDB is being updated regularly.
FPC Web Viewer is a Java-based tool to view FPC data and contig maps. Now it's available to view the FPC Contig maps and data in wheat D-genome physical mappingand several other FPC projects.
302,976 Ae. tauschii BAC and BIBAC clones in five BAC/BIBAC libraries, representing a 8.5x coverage of the wheat D genome, have been developed. Please see details.

Last modified on May 28, 2004
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